a patient who is taking metformin to treat type 2 diabetes This is a topic that many people are looking for. thevoltreport.com is a channel providing useful information about learning, life, digital marketing and online courses …. it will help you have an overview and solid multi-faceted knowledge . Today, thevoltreport.com would like to introduce to you Metformin: Its the First Choice. Following along are instructions in the video below:
Has been the first choice for diabetes treatment for a long time. And itss a consensus first choice. Everyone pretty much agrees that it should be the first the reason for that choice is that it really fulfills all of the kind of checkmarks that youd like for a drug for a very common disease.
Its effective at lowering hemoglobin a1c. Usually by about 1 percent. Its very well tolerated and its incredibly safe the final added bonus is that its really really cheap.
Metformins been around for more than five decades and its cost is among the lowest of any prescription drug in the world. The major concerns about metformin in the past have been around the issue of lactic acidosis. Which is a very severe condition which can lead to mortality.
But it is just vanishingly rare with metformin compared with its predecessor phenformin where it was substantially more common otherwise. Metformin is really well tolerated it causes in probably. 5 to 10 percent of patients.
Some gastric disturbance a sense of fullness sometimes some soft bowel movements. But otherwise. Its incredibly well tolerated and very safe.
The question with diabetes treatment has really gone from whether how you treat people. First. Which is usually with lifestyle intervention trying to get people to lose weight increase their activity levels and now more recently.
Weve advised that people start on metformin. Very early in the course even at the same time as they try to lose weight. Because one of its advantages is that it can help with some weight loss in past it used to be that wed always try lifestyle intervention first with the goal of losing weight increasing activity levels.
But now even many groups are suggesting that metformin be started very early on right at the time when you identify diabetes. Even as youre introducing lifestyle intervention. One of the reasons for that is that metformin is at worst weight neutral and in most studies leads to the loss of you know.
4 to 5 pounds. So thats an added benefit unless. There is a contraindication specific contraindication for a patient to not be on metformin virtually everyone with type 2 diabetes should be on metformin over the course of their disease.
Sometimes as people get older. If they develop kidney dysfunction. We may need to stop it.
But otherwise for the most part it should be started and then continued over the lifespan of their diabetes. Metformin. Has been studied in the diabetes prevention program.
Extensively and of note. Its one of the only now its a repurposed drug. I mean metformin in a sense has been used to treat type 2 diabetes of course.
But has not been approved and it is not currently labeled for prevention. Thats important to know. But one of our health economic analyses demonstrated that metformin actually is cost saving in the sense of when we looked at the costs of medical care in our patients who were treated with metformin in part because metformin is so inexpensive and because it reduced the need for blood pressure medicines and other medications.
That it actually was cost saving and thats remarkable. Theres hardly any drug on the planet. Which looks like its cost saving.
But metformin may be kind of an old drug. A 60 year old drug. That is a wonder drug of the 21st century .
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